She wants to be happy and sweet, but it's just too hard right now. In a few days she will feel better as her body gains a proper balance and the steroids slow the diarrhea. She has been so cute with her gluten free diet, doing very well, with the exception of her finding frosted mini-wheat cereal in the pantry with Evie, the two of them had their very own picnic on the pantry floor. I know the more we pursue this GF diet the easier it will get; including the absence of gluten containing foods in the pantry that she can access. Everything gets easier with time...right? ;)
The most recent plan for Alice's future is to drag our feet as long as possible and hope the steroids will get her back to baseline, as we contemplate the next step. Because she has warm antibodies (indication that still remains the host/original antibodies), we will have to depend on time even more. Time is a tool we hope to use in regards to her original antibodies (life span), in which have been less responsive to the chemo and other therapies. At least for now this is a less abrasive approach, until further information is available.
I included a little about warm antibodies from Wikipedia, for my journal purposes and to help explain what a warm antibody is for anyone who wants to know.
The most common antibody involved in warm antibody AIHA is IgG, though sometimes IgA is found. The IgG antibodies attach to a red blood cell, leaving their FC portion exposed with maximal reactivity at 37°C (versus cold antibody induced hemolytic anemia whose antibodies only bind red blood cells at low body temperatures, typically 28-31°C). The FCregion is recognized and grabbed onto by FC receptors found on monocytes and macrophages in the spleen. These cells will pick off portions of the red cell membrane, almost like they are taking a bite. The loss of membrane causes the red blood cells to become spherocytes. Spherocytes are not as flexible as normal RBCs, and will be singled-out for destruction in the red pulp of the spleen as well as other portions of the reticuloendothelial system. The red blood cells trapped in the spleen cause the spleen to enlarge, leading to the splenomegaly often seen in these patients.
|just loving Dad|
|After a 3 am admission, she is exhausted|
|Opps... learning to us a spoon and having fun in the process|
|chocolate pudding party for Evie ended on a bad note|